Gaussian curvature and the budding kinetics of enveloped viruses.

The formation of a membrane-enveloped virus starts with the assembly of a curved layer of capsid proteins lining the interior of the plasma membrane (PM) of the host cell. This layer develops into a spherical shell (capsid) enveloped by a lipid-rich membrane. In many cases, the budding process stall...

Full description

Bibliographic Details
Main Authors: Sanjay Dharmavaram, Selene Baochen She, Guillermo Lázaro, Michael Francis Hagan, Robijn Bruinsma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-08-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1006602