S-nitroso-N-acetylcysteine ameliorates ischemia-reperfusion injury in the steatotic liver

S-nitroso-N-acetylcysteine ameliorates ischemia-reperfusion injury in the steatotic liver

BACKGROUND: Steatosis is currently the most common chronic liver disease and it can aggravate ischemia-reperfusion (IR) lesions. We hypothesized that S-nitroso-N-acetylcysteine (SNAC), an NO donor component, can ameliorate cell damage from IR injury. In this paper, we report the effect of SNAC on li...

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Bibliographic Details
Main Authors: Wellington Andraus, Gabriela Freitas Pereira de Souza, Marcelo Ganzarolli de Oliveira, Luciana B. P. Haddad, Ana Maria M. Coelho, Flavio Henrique Galvão, Regina Maria Cubero Leitão, Luiz Augusto Carneiro D'Albuquerque, Marcel Cerqueira Cesar Machado
Format: Article
Language:English
Published: Faculdade de Medicina / USP 2010-01-01
Series:Clinics
Subjects:
Fatty liver
S-nitrosothiol
S-nitroso-N-acetylcysteine
reperfusion injury
oxidative stress
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322010000700011

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322010000700011

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