The ins and outs of vanillyl alcohol oxidase: Identification of ligand migration paths.

Vanillyl alcohol oxidase (VAO) is a homo-octameric flavoenzyme belonging to the VAO/PCMH family. Each VAO subunit consists of two domains, the FAD-binding and the cap domain. VAO catalyses, among other reactions, the two-step conversion of p-creosol (2-methoxy-4-methylphenol) to vanillin (4-hydroxy-...

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Bibliographic Details
Main Authors: Gudrun Gygli, Maria Fátima Lucas, Victor Guallar, Willem J H van Berkel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-10-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1005787