Concepts of extracellular matrix remodelling in tumour progression and metastasis

Tumors are more than cancer cells — the extracellular matrix is a protein structure that organizes all tissues and is altered in cancer. Here, the authors review recent progress in understanding how the cancer cells and tumor-associated stroma cells remodel the extracellular matrix to drive tumor gr...

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Bibliographic Details
Main Authors: Juliane Winkler, Abisola Abisoye-Ogunniyan, Kevin J. Metcalf, Zena Werb
Format: Article
Language:English
Published: Nature Publishing Group 2020-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-18794-x