Comparison of the free and total light chain assays in serum and urine samples with immunofixation electrophoresis for detecting monoclonal proteins in patients with monoclonal gammopathy

Comparison of the free and total light chain assays in serum and urine samples with immunofixation electrophoresis for detecting monoclonal proteins in patients with monoclonal gammopathy

Monoclonal protein (M-protein) is produced by a malignant clone of plasma cells. Detected in serum and/or urine, this typically indicates multiple myeloma (MM) or other monoclonal gammopathy (MG). In a majority of MM cases, with the production of intact monoclonal immunoglobulin (Ig), malignant plas...

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Bibliographic Details
Main Authors: Korpysz Maciej, Morawska Marta, Burska Agata, Donica Helena
Format: Article
Language:English
Published: Sciendo 2014-09-01
Series:Current Issues in Pharmacy and Medical Sciences
Subjects:
free light chains
total light chains
monoclonal gammopathy
multiple myeloma
immunofixation
Online Access:https://doi.org/10.1515/cipms-2015-0008

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