Effect of Platelet Rich Fibrin (PRF) on Peri-implant Soft Tissue and Crestal Bone in One-Stage Implant Placement: A Randomized Controlled Trial
Introduction: The viability of Platelet Rich Fibrin (PRF) on enhancement of osseous and associated tissue healing has been substantiated well in literature. However, paucity in the applicability of PRF to enhance peri-implant healing in oral region is not wellcorroborated. Purpose: This prospect...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2015-04-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/5788/12636_CE(RA1)_F(T)_PF1(PAK)_PFA(P)_PF2(PAG).pdf |
| Summary: | Introduction: The viability of Platelet Rich Fibrin (PRF) on
enhancement of osseous and associated tissue healing has been
substantiated well in literature. However, paucity in the applicability
of PRF to enhance peri-implant healing in oral region is not wellcorroborated.
Purpose: This prospective study evaluated the effect of Platelet
PRF on peri-implant tissue response following one-stage implant
placement with non-functional immediate provisionalization in
maxillary anterior region.
Materials and Methods: A Prospective, Randomized Controlled
Trial (RCT) was conducted across 20 (15 male, 5 Female)
systemically healthy subjects with maintainable oral hygiene.
Subjects were broadly divided into two groups i.e. Study group
(PRF group) and Control group (Non-PRF group). Twenty standard
SLA- AB/AE (alumina oxide blasted/acid etched surface treated)
tapered threaded dental implants were randomly placed with and
without PRF and immediately provisionalized. The subjects were
evaluated clinically and radiographically at baseline (at time of
implant placement), one month and three month post-operatively
for peri-implant soft tissue and crestal bone responses.
Results: At 3 months, all implants remained osseointegrated.
The mean marginal bone changes were observed from baseline
to 3 months in both groups with lesser changes observed in PRF
Group. No significant differences in probing depth and bleeding on
probing were noted during follow-up.
Conclusion: Within the limitations of this study, PRF could be
considered as a healing biomaterial with potential beneficial effect
on peri-implant tissue and can be used as a therapeutic adjuvant
in clinical scenario of one stage, single tooth implant placement
procedure in maxillary anterior region. |
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| ISSN: | 2249-782X 0973-709X |