Tissue Microarrays, A Revolution in Pathology Research

A long-lasting problem in the analysis of tissue samples is the time-consuming and repetitive process of histologic preparation and pathologic review of tissue sections. These two critical factors, innate nonuniformity in preparation and subjectivity of analysis, therefore limit the scientific and...

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Main Authors: Elham Kalantari, Zahra Madjd
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2014-01-01
Series:Basic & Clinical Cancer Research
Subjects:
Online Access:https://bccr.tums.ac.ir/index.php/bccrj/article/view/64
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spelling doaj-64b6a377018d4659a001b8ae45324be62021-04-04T07:07:50ZengTehran University of Medical SciencesBasic & Clinical Cancer Research2228-65272228-54662014-01-0161Tissue Microarrays, A Revolution in Pathology ResearchElham Kalantari0Zahra Madjd1Oncopathology Research Center, Iran University of Medical Sciences, TehranOncopathology Research Center, Iran University of Medical Sciences, Tehran AND Department of Pathology, Iran University of Medical Sciences, Tehran AND Department of Molecular Medicine, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences, Tehran A long-lasting problem in the analysis of tissue samples is the time-consuming and repetitive process of histologic preparation and pathologic review of tissue sections. These two critical factors, innate nonuniformity in preparation and subjectivity of analysis, therefore limit the scientific and statistical thoroughness of tissue based studies. Employing tissue microarray (TMA) technique provides a potential solution to each of these problems. This review discusses the methods of creating tissue microarrays, the advantages and disadvantages of the technology, analysis methods, and recent TMA applications. https://bccr.tums.ac.ir/index.php/bccrj/article/view/64#No Keywords#
collection DOAJ
language English
format Article
sources DOAJ
author Elham Kalantari
Zahra Madjd
spellingShingle Elham Kalantari
Zahra Madjd
Tissue Microarrays, A Revolution in Pathology Research
Basic & Clinical Cancer Research
#No Keywords#
author_facet Elham Kalantari
Zahra Madjd
author_sort Elham Kalantari
title Tissue Microarrays, A Revolution in Pathology Research
title_short Tissue Microarrays, A Revolution in Pathology Research
title_full Tissue Microarrays, A Revolution in Pathology Research
title_fullStr Tissue Microarrays, A Revolution in Pathology Research
title_full_unstemmed Tissue Microarrays, A Revolution in Pathology Research
title_sort tissue microarrays, a revolution in pathology research
publisher Tehran University of Medical Sciences
series Basic & Clinical Cancer Research
issn 2228-6527
2228-5466
publishDate 2014-01-01
description A long-lasting problem in the analysis of tissue samples is the time-consuming and repetitive process of histologic preparation and pathologic review of tissue sections. These two critical factors, innate nonuniformity in preparation and subjectivity of analysis, therefore limit the scientific and statistical thoroughness of tissue based studies. Employing tissue microarray (TMA) technique provides a potential solution to each of these problems. This review discusses the methods of creating tissue microarrays, the advantages and disadvantages of the technology, analysis methods, and recent TMA applications.
topic #No Keywords#
url https://bccr.tums.ac.ir/index.php/bccrj/article/view/64
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