Established Beta Amyloid Pathology Is Unaffected by TREM2 Elevation in Reactive Microglia in an Alzheimer’s Disease Mouse Model

Several genetic studies have identified a rare variant of triggering receptor expressed on myeloid cells 2 (TREM2) as a risk factor for Alzheimer’s disease (AD). However, findings on the effects of TREM2 on Aβ deposition are quite inconsistent in animal studies, requiring further investigation. In t...

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Bibliographic Details
Main Authors: Qiuju Yuan, Xiaodong Liu, Yi Zhang, Yan-Fang Xian, Juntao Zou, Xie Zhang, Pengyun Huang, You-Qiang Song, Zhi-Xiu Lin
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/26/9/2685