Efektivitas Terapi Kortikosteroid Intranasal pada Hipertrofi Adenoid Usia Dewasa berdasarkan Pemeriksaan Narrow Band Imaging

• Main Authors: Sinta Sari Ratunanda, Jipie Iman Satriyo, Dindy Samiadi, Teti Madiadipoera, Ratna Anggraeni
• Format: Article
• Language: English
• Published: Universitas Padjajaran 2016-12-01
• Series: Majalah Kedokteran Bandung
• Subjects: Adenoid hypertrophy; intranasal corticosteroids; narrow band imaging
• Online Access: http://journal.fk.unpad.ac.id/index.php/mkb/article/view/914

Adenoid hypertrophy is a process in which adenoid size becomes enlarged and causes clinical symptoms, especially nasal obstruction. Adenoid hypertrophy can be due to physiological, inflammatory, or malignancy processes. Adenoid inflammatory process can be assessed using a flexible fiberoptic nasoendoscopy with narrow band imaging (NBI). Intranasal corticosteroid is one of the choices to treat adenoid hypertrophy in children; however, more experiments are needed to use it in adults. This study was performed in the period of November 2012 to January 2013 at the outpatient clinic of the Otorhinolaryngology-Head and Neck Surgery Department of Dr. Hasan Sadikin General Hospital Bandung, using pre- and post-test open-labeled quasiexperimental design. Sample was selected through consecutive sampling, involving 11 subjects. Diagnosis was based on research subject’s anamnesis, ear nose and throat (ENT) physical examination, NBI-equipped fiberoptic nasoendocopy examination, and adenoid mucosal biopsy. Subjects were given intranasal corticosteroid therapy for four weeks. NBI-equipped fiberoptic nasoendocopy examination and biopsy examination were performed after therapy. Data were analyzed using Wilcoxon test, showing significant improvement of the adenoid inflammation after intranasal corticosteroids therapy (p<0.05). McNemar test results showed a significant reduction in adenoid size (p<0.05). Spearman rank test showed a significant correlation between histopathologic findings and NBI examination result (p<0.05). In conclusion, intranasal corticosteroids are effective for adult adenoid hypertrophy treatment based on NBI examination. [MKB. 2016;48(4):228–33]