Identification of Kaurane-Type Diterpenes as Inhibitors of Leishmania Pteridine Reductase I

Identification of Kaurane-Type Diterpenes as Inhibitors of Leishmania Pteridine Reductase I

The current treatments against <i>Leishmania</i> parasites present high toxicity and multiple side effects, which makes the control and elimination of leishmaniasis challenging. Natural products constitute an interesting and diverse chemical space for the identification of new antileishm...

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Bibliographic Details
Main Authors: Chonny Herrera-Acevedo, Areli Flores-Gaspar, Luciana Scotti, Francisco Jaime Bezerra Mendonça-Junior, Marcus Tullius Scotti, Ericsson Coy-Barrera
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Molecules
Subjects:
<i>Leishmania</i>
natural products
kauranes
Asteraceae
virtual screening
machine learning
Online Access:https://www.mdpi.com/1420-3049/26/11/3076

Internet

https://www.mdpi.com/1420-3049/26/11/3076

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