B7-H3 Promotes Prostate Cancer Progression in Mice by Antagonizing Myeloid-Derived Suppressor Cell Apoptosis

Background: B7-H3 is an important immunomodulatory molecule, and clinical studies have confirmed that its expression level is closely correlated with prostate cancer prognosis. However, the mechanism of its biological action is unclear. Methods: An engineered cell line overexpressing B7-H3 was const...

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Bibliographic Details
Main Authors: Yunfen Zhou MD, Guangbo Zhang PhD, Weijie Zhang PhD, Xuedong Wei PhD, Jianquan Hou PhD, Yuhua Huang PhD
Format: Article
Language:English
Published: SAGE Publishing 2020-12-01
Series:Technology in Cancer Research & Treatment
Online Access:https://doi.org/10.1177/1533033820971649