Phosphatidic acid modulation of Kv channel voltage sensor function

Phosphatidic acid modulation of Kv channel voltage sensor function

Membrane phospholipids can function as potent regulators of ion channel function. This study uncovers and investigates the effect of phosphatidic acid on Kv channel gating. Using the method of reconstitution into planar lipid bilayers, in which protein and lipid components are defined and controlled...

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Bibliographic Details
Main Authors: Richard K Hite, Joel A Butterwick, Roderick MacKinnon
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-10-01
Series:eLife
Subjects:
ion channel
electrophysiology
voltage-gated potassium channel
Online Access:https://elifesciences.org/articles/04366

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