Automated Classification and Cluster Visualization of Genotypes Derived from High Resolution Melt Curves.

Automated Classification and Cluster Visualization of Genotypes Derived from High Resolution Melt Curves.

High Resolution Melting (HRM) following PCR has been used to identify DNA genotypes. Fluorescent dyes bounded to double strand DNA lose their fluorescence with increasing temperature, yielding different signatures for different genotypes. Recent software tools have been made available to aid in the...

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Bibliographic Details
Main Authors:	Sami Kanderian, Lingxia Jiang, Ivor Knight
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2015-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC4659556?pdf=render

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