Regulation of vascular smooth muscle tone by adipose-derived contracting factor.

Obesity and arterial hypertension, important risk factors for atherosclerosis and coronary artery disease, are characterized by an increase in vascular tone. While obesity is known to augment vasoconstrictor prostanoid activity in endothelial cells, less is known about factors released from fat tiss...

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Bibliographic Details
Main Authors: Matthias R Meyer, Natalie C Fredette, Matthias Barton, Eric R Prossnitz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3823600?pdf=render