Structural heterogeneity of α-synuclein fibrils amplified from patient brain extracts
Parkinson’s disease (PD) and Multiple System Atrophy (MSA) are characterized by the pathological accumulation of α-synuclein. Here the authors employ fluorescent probes, electron microscopy and NMR spectroscopy to study the properties of α-synuclein aggregates that were amplified from patient brain...
Full description
Bibliographic Details
| Main Authors: |
Timo Strohäker,
Byung Chul Jung,
Shu-Hao Liou,
Claudio O. Fernandez,
Dietmar Riedel,
Stefan Becker,
Glenda M. Halliday,
Marina Bennati,
Woojin S. Kim,
Seung-Jae Lee,
Markus Zweckstetter |
|---|
| Format: | Article
|
|---|
| Language: | English |
|---|
| Published: |
Nature Publishing Group
2019-12-01
|
|---|
| Series: | Nature Communications
|
|---|
| Online Access: | https://doi.org/10.1038/s41467-019-13564-w
|
|---|
