Adolescent-onset anti-MDA5 antibody-positive juvenile dermatomyositis with rapidly progressive interstitial lung disease and spontaneous pneumomediastinum: a case report and literature review

Adolescent-onset anti-MDA5 antibody-positive juvenile dermatomyositis with rapidly progressive interstitial lung disease and spontaneous pneumomediastinum: a case report and literature review

Abstract Background Dermatomyositis with positive anti-melanoma differentiation-associated gene 5 (anti-MDA5) antibody has a distinct phenotype associated with small hand joint arthritis, mucocutaneous ulceration, palmar papules and less muscle involvement. It is also associated with increased risk...

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Bibliographic Details
Main Authors:	Tsz-Wing Yeung, Kai-Ning Cheong, Yu-Lung Lau, Kei-Chiu Niko Tse
Format:	Article
Language:	English
Published:	BMC 2021-06-01
Series:	Pediatric Rheumatology Online Journal
Subjects:	Juvenile dermatomyositis Anti-melanoma differentiation-associated gene 5 antibody Interstitial lung disease Pneumomediastinum Myositis-specific antibodies
Online Access:	https://doi.org/10.1186/s12969-021-00595-1

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