Microfluidics-based assay on the effects of microenvironmental geometry and aqueous flow on bacterial adhesion behaviors

A new microfluidic system with four different microchambers (a circle and three equilateral concave polygons) was designed and fabricated using poly(dimethylsiloxane) (PDMS) and the soft lithography method. Using this microfluidic device at six flow rates (5, 10, 20, 30, 40, and 50 μL/h), the effe...

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Bibliographic Details
Main Authors: Yang Liu, Jian-Chun Wang, Li Ren, Qin Tu, Wen-Ming Liu, Xue-Qin Wang, Rui Liu, Yan-Rong Zhang, Jin-Yi Wang
Format: Article
Language:English
Published: Elsevier 2011-08-01
Series:Journal of Pharmaceutical Analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177911000049