Anti-prion drug mPPIg5 inhibits PrP(C) conversion to PrP(Sc).

Anti-prion drug mPPIg5 inhibits PrP(C) conversion to PrP(Sc).

Prion diseases, also known as transmissible spongiform encephalopathies, are a group of fatal neurodegenerative diseases that include scrapie in sheep, bovine spongiform encephalopathy (BSE) in cattle and Creutzfeldt-Jakob disease (CJD) in humans. The 'protein only hypothesis' advocates th...

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Bibliographic Details
Main Authors: James M McCarthy, Markus Franke, Ulrike K Resenberger, Sibeal Waldron, Jeremy C Simpson, Jörg Tatzelt, Dietmar Appelhans, Mark S Rogers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3557256?pdf=render

Internet

http://europepmc.org/articles/PMC3557256?pdf=render

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