Improving the flux distributions simulated with genome-scale metabolic models of Saccharomyces cerevisiae

Genome-scale metabolic models (GEMs) can be used to evaluate genotype-phenotype relationships and their application to microbial strain engineering is increasing in popularity. Some of the algorithms used to simulate the phenotypes of mutant strains require the determination of a wild-type flux dist...

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Bibliographic Details
Main Authors: Rui Pereira, Jens Nielsen, Isabel Rocha
Format: Article
Language:English
Published: Elsevier 2016-12-01
Series:Metabolic Engineering Communications
Online Access:http://www.sciencedirect.com/science/article/pii/S2214030116300141