Export of piRNA precursors by EJC triggers assembly of cytoplasmic Yb-body in Drosophila

Export of piRNA precursors by EJC triggers assembly of cytoplasmic Yb-body in Drosophila

In Drosophila ovarian follicle cells, piRNAs generated from RNA precursors are processed in cytoplasmic Yb-bodies. The authors identify the exportin and the exon junction complexes as required to transfer precursors to cytoplasm. They also show that Yb-body formation requires piRNA precursor export.

Bibliographic Details
Main Authors: Cynthia Dennis, Emilie Brasset, Arpita Sarkar, Chantal Vaury
Format: Article
Language:English
Published: Nature Publishing Group 2016-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms13739
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spelling doaj-64326cb5b1554498bf4fb8693f6e98fb2021-05-11T10:46:59ZengNature Publishing GroupNature Communications2041-17232016-12-017111210.1038/ncomms13739Export of piRNA precursors by EJC triggers assembly of cytoplasmic Yb-body in DrosophilaCynthia Dennis0Emilie Brasset1Arpita Sarkar2Chantal Vaury3Univ Clermont Auvergne, CNRS, INSERM, GReD, BP 10448Univ Clermont Auvergne, CNRS, INSERM, GReD, BP 10448Univ Clermont Auvergne, CNRS, INSERM, GReD, BP 10448Univ Clermont Auvergne, CNRS, INSERM, GReD, BP 10448In Drosophila ovarian follicle cells, piRNAs generated from RNA precursors are processed in cytoplasmic Yb-bodies. The authors identify the exportin and the exon junction complexes as required to transfer precursors to cytoplasm. They also show that Yb-body formation requires piRNA precursor export.https://doi.org/10.1038/ncomms13739
collection DOAJ
language English
format Article
sources DOAJ
author Cynthia Dennis
Emilie Brasset
Arpita Sarkar
Chantal Vaury
spellingShingle Cynthia Dennis
Emilie Brasset
Arpita Sarkar
Chantal Vaury
Export of piRNA precursors by EJC triggers assembly of cytoplasmic Yb-body in Drosophila
Nature Communications
author_facet Cynthia Dennis
Emilie Brasset
Arpita Sarkar
Chantal Vaury
author_sort Cynthia Dennis
title Export of piRNA precursors by EJC triggers assembly of cytoplasmic Yb-body in Drosophila
title_short Export of piRNA precursors by EJC triggers assembly of cytoplasmic Yb-body in Drosophila
title_full Export of piRNA precursors by EJC triggers assembly of cytoplasmic Yb-body in Drosophila
title_fullStr Export of piRNA precursors by EJC triggers assembly of cytoplasmic Yb-body in Drosophila
title_full_unstemmed Export of piRNA precursors by EJC triggers assembly of cytoplasmic Yb-body in Drosophila
title_sort export of pirna precursors by ejc triggers assembly of cytoplasmic yb-body in drosophila
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2016-12-01
description In Drosophila ovarian follicle cells, piRNAs generated from RNA precursors are processed in cytoplasmic Yb-bodies. The authors identify the exportin and the exon junction complexes as required to transfer precursors to cytoplasm. They also show that Yb-body formation requires piRNA precursor export.
url https://doi.org/10.1038/ncomms13739
work_keys_str_mv AT cynthiadennis exportofpirnaprecursorsbyejctriggersassemblyofcytoplasmicybbodyindrosophila
AT emiliebrasset exportofpirnaprecursorsbyejctriggersassemblyofcytoplasmicybbodyindrosophila
AT arpitasarkar exportofpirnaprecursorsbyejctriggersassemblyofcytoplasmicybbodyindrosophila
AT chantalvaury exportofpirnaprecursorsbyejctriggersassemblyofcytoplasmicybbodyindrosophila
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