Mechanism of hepatitis B virus X inducing hepatocellular carcinoma in mice through COX-2 and its downstream factors

Mechanism of hepatitis B virus X inducing hepatocellular carcinoma in mice through COX-2 and its downstream factors

Objective To investigate the dynamic changes and the roles of COX-2 and its downstream factors in the carcinogenic process using a mouse model stably expressing hepatitis B virus X (HBx). Methods The expression of HBx in HBx-EGFP-14-19 cells was detected by Western blotting and RT-qPCR. A mouse mode...

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Bibliographic Details
Main Authors: WU Nan, ZHOU Mengyao1, DU Bin, HUANG Xin, ZHANG Siyao, KUANG Qin, , WU Yong, FENG Tao
Format: Article
Language:zho
Published: Editorial Office of Journal of Third Military Medical University 2021-05-01
Series:Di-san junyi daxue xuebao
Subjects:
hepatitis b virus x
liver cancer
cox-2
apoptosis
animal model
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/202011103.htm

Internet

http://aammt.tmmu.edu.cn/Upload/rhtml/202011103.htm

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