Glucosylceramides From Lomentospora prolificans Induce a Differential Production of Cytokines and Increases the Microbicidal Activity of Macrophages

Glucosylceramides From Lomentospora prolificans Induce a Differential Production of Cytokines and Increases the Microbicidal Activity of Macrophages

Lomentospora prolificans is an emerging opportunistic fungus with a high resistance to antifungal agents and it can cause localized infections in immunocompetent patients and disseminated infections with a high mortality rate in immunosuppressed patients. Glucosylceramides (GlcCer) are synthetized i...

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Bibliographic Details
Main Authors: Mariana Ingrid Dutra da Silva Xisto, Julián Esteban Muñoz Henao, Lucas dos Santos Dias, Giulia Maria Pires Santos, Renata de Oliveira Rocha Calixto, Mariana Collodetti Bernardino, Carlos Pelleschi Taborda, Eliana Barreto-Bergter
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Microbiology
Subjects:
Lomentospora prolificans
glucosylceramides
GlcCer
structural characterization
innate immune response
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.00554/full

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