Metabolomic analysis and mass spectrometry imaging after neonatal stroke and cell therapies in mouse brains
Abstract Ischemic brain injury provokes complex, time-dependent downstream pathways that ultimately lead to cell death. We aimed to demonstrate the levels of a wide range of metabolites in brain lysates and their on-tissue distribution following neonatal stroke and cell therapies. Postnatal day 12 m...
Main Authors: | Emi Tanaka, Yuko Ogawa, Ritsuko Fujii, Tomomi Shimonaka, Yoshiaki Sato, Takashi Hamazaki, Tokiko Nagamura-Inoue, Haruo Shintaku, Masahiro Tsuji |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2020-12-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-020-78930-x |
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