Replication and recombination factors contributing to recombination-dependent bypass of DNA lesions by template switch.
Damage tolerance mechanisms mediating damage-bypass and gap-filling are crucial for genome integrity. A major damage tolerance pathway involves recombination and is referred to as template switch. Template switch intermediates were visualized by 2D gel electrophoresis in the proximity of replication...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2010-11-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC2978687?pdf=render |