Variant on Manifestation of Duodenal Metastasis 26 Years after Initial Diagnosis of Primary Cutaneous Melanoma
Malignant duodenal neoplasms are relatively rare, and the diagnosis is often delayed because of their vague and nonspecific symptoms. We report the case of a 79-year-old female who had a medical history of malignant melanoma of the cheek that had initially been diagnosed at 53 years of age. Work-up...
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Karger Publishers
2010-03-01
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| Series: | Case Reports in Gastroenterology |
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| Online Access: | http://www.karger.com/Article/FullText/290383 |
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doaj-6418536329764cb6864bbdb85572c2c72020-11-24T21:18:17ZengKarger PublishersCase Reports in Gastroenterology1662-06312010-03-0141939910.1159/000290383290383Variant on Manifestation of Duodenal Metastasis 26 Years after Initial Diagnosis of Primary Cutaneous MelanomaKumiko KitajimaArmelle Bardier-DupasSylvie BretonGéraldine RousseauJean-Michel SiksikJean-Christophe VaillantLaurent HannounMalignant duodenal neoplasms are relatively rare, and the diagnosis is often delayed because of their vague and nonspecific symptoms. We report the case of a 79-year-old female who had a medical history of malignant melanoma of the cheek that had initially been diagnosed at 53 years of age. Work-up revealed severe stenosis of the duodenum caused by a large mass with ulceration at the tip of its mucosal surface. Tumor biopsy led to a histological diagnosis of extremely poorly differentiated carcinoma, but it was impossible to determine whether the lesion was a primary neoplasm or represented secondary involvement. Pancreatoduodenectomy was performed, and the surgical specimen showed a protuberant tumor in the nonampullary region of the second portion of the duodenum. Final diagnosis of metastatic duodenal melanoma was made by immunohistological examination. She is currently alive without recurrence 28 months after the surgical treatment.http://www.karger.com/Article/FullText/290383Nonampullary duodenal neoplasmAmelanotic melanomaMetastatic duodenal tumorMalignant melanoma |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Kumiko Kitajima Armelle Bardier-Dupas Sylvie Breton Géraldine Rousseau Jean-Michel Siksik Jean-Christophe Vaillant Laurent Hannoun |
| spellingShingle |
Kumiko Kitajima Armelle Bardier-Dupas Sylvie Breton Géraldine Rousseau Jean-Michel Siksik Jean-Christophe Vaillant Laurent Hannoun Variant on Manifestation of Duodenal Metastasis 26 Years after Initial Diagnosis of Primary Cutaneous Melanoma Case Reports in Gastroenterology Nonampullary duodenal neoplasm Amelanotic melanoma Metastatic duodenal tumor Malignant melanoma |
| author_facet |
Kumiko Kitajima Armelle Bardier-Dupas Sylvie Breton Géraldine Rousseau Jean-Michel Siksik Jean-Christophe Vaillant Laurent Hannoun |
| author_sort |
Kumiko Kitajima |
| title |
Variant on Manifestation of Duodenal Metastasis 26 Years after Initial Diagnosis of Primary Cutaneous Melanoma |
| title_short |
Variant on Manifestation of Duodenal Metastasis 26 Years after Initial Diagnosis of Primary Cutaneous Melanoma |
| title_full |
Variant on Manifestation of Duodenal Metastasis 26 Years after Initial Diagnosis of Primary Cutaneous Melanoma |
| title_fullStr |
Variant on Manifestation of Duodenal Metastasis 26 Years after Initial Diagnosis of Primary Cutaneous Melanoma |
| title_full_unstemmed |
Variant on Manifestation of Duodenal Metastasis 26 Years after Initial Diagnosis of Primary Cutaneous Melanoma |
| title_sort |
variant on manifestation of duodenal metastasis 26 years after initial diagnosis of primary cutaneous melanoma |
| publisher |
Karger Publishers |
| series |
Case Reports in Gastroenterology |
| issn |
1662-0631 |
| publishDate |
2010-03-01 |
| description |
Malignant duodenal neoplasms are relatively rare, and the diagnosis is often delayed because of their vague and nonspecific symptoms. We report the case of a 79-year-old female who had a medical history of malignant melanoma of the cheek that had initially been diagnosed at 53 years of age. Work-up revealed severe stenosis of the duodenum caused by a large mass with ulceration at the tip of its mucosal surface. Tumor biopsy led to a histological diagnosis of extremely poorly differentiated carcinoma, but it was impossible to determine whether the lesion was a primary neoplasm or represented secondary involvement. Pancreatoduodenectomy was performed, and the surgical specimen showed a protuberant tumor in the nonampullary region of the second portion of the duodenum. Final diagnosis of metastatic duodenal melanoma was made by immunohistological examination. She is currently alive without recurrence 28 months after the surgical treatment. |
| topic |
Nonampullary duodenal neoplasm Amelanotic melanoma Metastatic duodenal tumor Malignant melanoma |
| url |
http://www.karger.com/Article/FullText/290383 |
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