Enhanced inhibition of murine prostatic carcinoma growth by immunization with or administration of viable human umbilical vein endothelial cells and CRM197

Enhanced inhibition of murine prostatic carcinoma growth by immunization with or administration of viable human umbilical vein endothelial cells and CRM197

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Vaccination with xenogeneic and syngeneic endothelial cells is effective for inhibiting tumor growth. Nontoxic diphtheria toxin (CRM197), as an immunogen or as a specific inhibitor of heparin-binding EGF-like growth factor, has shown promising antitumor activity. Therefore, immunization wi...

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Bibliographic Details
Main Authors: Zhang Huiyong, Lu Yong, Mekoo Didier, Zhang Yu, Fang Jing, Cao Rongyue, Liu Jingjing
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2011-02-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
RM-1 prostatic carcinoma
CRM197
Immunization
Human umbilical vein endothelial cells
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000200008

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