Analysis of the role of interleukin 6 receptor haplotypes in the regulation of circulating levels of inflammatory biomarkers and risk of coronary heart disease.

Analysis of the role of interleukin 6 receptor haplotypes in the regulation of circulating levels of inflammatory biomarkers and risk of coronary heart disease.

Variants at the interleukin 6 receptor (IL6R) gene regulate inflammation and are associated with risk of coronary heart disease (CHD). The aim of the present study was to investigate the effects of IL6R haplotypes on circulating levels of inflammatory biomarkers and risk of CHD. We performed a disco...

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Main Authors: Bruna Gigante, Rona J Strawbridge, Ilais Moreno Velasquez, Zahra Golabkesh, Angela Silveira, Anuj Goel, Damiano Baldassarre, Fabrizio Veglia, Elena Tremoli, Robert Clarke, Hugh Watkins, Anders Hamsten, Steve E Humphries, Ulf de Faire
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4364007?pdf=render

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