Functional Screening Techniques to Identify Long Non-Coding RNAs as Therapeutic Targets in Cancer

Functional Screening Techniques to Identify Long Non-Coding RNAs as Therapeutic Targets in Cancer

Recent technological advancements such as CRISPR/Cas-based systems enable multiplexed, high-throughput screening for new therapeutic targets in cancer. While numerous functional screens have been performed on protein-coding genes to date, long non-coding RNAs (lncRNAs) represent an emerging class of...

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Bibliographic Details
Main Authors: Kathleen M. Lucere, Megan M. R. O’Malley, Sarah D. Diermeier
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cancers
Subjects:
long non-coding RNA (lncRNA)
cancer
oncology
CRISPR
functional screening
siRNA
Online Access:https://www.mdpi.com/2072-6694/12/12/3695

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