Advantages of Using Paclitaxel in Combination with Oncolytic Adenovirus Utilizing RNA Destabilization Mechanism

Advantages of Using Paclitaxel in Combination with Oncolytic Adenovirus Utilizing RNA Destabilization Mechanism

Oncolytic virotherapy is a novel approach to cancer therapy. Ad-<i>fos</i>ARE is a conditionally replicative adenovirus engineered by inserting AU-rich elements (ARE) in the 3’-untranslated region of the E1A gene. In this study, we examined the oncolytic activity of Ad-<i>fos</i...

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Bibliographic Details
Main Authors: Elora Hossain, Umma Habiba, Aya Yanagawa-Matsuda, Arefin Alam, Ishraque Ahmed, Mohammad Towfik Alam, Motoaki Yasuda, Fumihiro Higashino
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cancers
Subjects:
Oncolytic adenovirus
E1A
AU-rich element (ARE), HuR
ARE-mRNA
Paclitaxel
Microtubules
Online Access:https://www.mdpi.com/2072-6694/12/5/1210

Internet

https://www.mdpi.com/2072-6694/12/5/1210

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