CAR-T in Cancer Treatment: Develop in Self-Optimization, Win-Win in Cooperation

CAR-T in Cancer Treatment: Develop in Self-Optimization, Win-Win in Cooperation

Despite remarkable achievements in the treatment of hematologic malignancies, chimeric antigen receptor (CAR)-T cell therapy still faces many obstacles. The limited antitumor activity and persistence of infused CAR-T cells, especially in solid tumors, are the main limiting factors for CAR-T therapy....

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Bibliographic Details
Main Authors: Feifei Guo, Jiuwei Cui
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cancers
Subjects:
chimeric antigen receptor T cell therapy
cancer immunotherapy
CAR structure
combined therapy
Online Access:https://www.mdpi.com/2072-6694/13/8/1955

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