Long read, isoform aware sequencing of mouse nucleus accumbens after chronic cocaine treatment
Abstract To better understand the full-length transcriptome of the nucleus accumbens (NAc)—a key brain reward region—in chronic cocaine treatment, we perform the first single molecule, long-read sequencing analysis using the Iso-seq method to detect 42,114 unique transcripts from mouse NAc polyadeny...
Main Authors: | Molly Estill, Efrain Ribeiro, Nancy J. Francoeur, Melissa L. Smith, Robert Sebra, Szu-Ying Yeh, Ashley M. Cunningham, Eric J. Nestler, Li Shen |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-03-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-86068-7 |
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