An Antigenic Thrift-Based Approach to Influenza Vaccine Design

An Antigenic Thrift-Based Approach to Influenza Vaccine Design

The antigenic drift theory states that influenza evolves via the gradual accumulation of mutations, decreasing a host’s immune protection against previous strains. Influenza vaccines are designed accordingly, under the premise of antigenic drift. However, a paradox exists at the centre of influenza...

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Bibliographic Details
Main Authors: Jai S. Bolton, Hannah Klim, Judith Wellens, Matthew Edmans, Uri Obolski, Craig P. Thompson
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Vaccines
Subjects:
vaccine
vaccination
influenza
evolutionary theory
antigenic drift
antigenic thrift
Online Access:https://www.mdpi.com/2076-393X/9/6/657

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