Earth Mover's Distance (EMD): A True Metric for Comparing Biomarker Expression Levels in Cell Populations.

Earth Mover's Distance (EMD): A True Metric for Comparing Biomarker Expression Levels in Cell Populations.

Changes in the frequencies of cell subsets that (co)express characteristic biomarkers, or levels of the biomarkers on the subsets, are widely used as indices of drug response, disease prognosis, stem cell reconstitution, etc. However, although the currently available computational "gating"...

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Main Authors: Darya Y Orlova, Noah Zimmerman, Stephen Meehan, Connor Meehan, Jeffrey Waters, Eliver E B Ghosn, Alexander Filatenkov, Gleb A Kolyagin, Yael Gernez, Shanel Tsuda, Wayne Moore, Richard B Moss, Leonore A Herzenberg, Guenther Walther
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4805242?pdf=render

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http://europepmc.org/articles/PMC4805242?pdf=render

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