Subcellular compartmentalization of docking protein-1 contributes to progression in colorectal cancer
Full-length (FL) docking protein-1 (DOK1) is an adapter protein which inhibits growth factor and immune response pathways in normal tissues, but is frequently lost in human cancers. Small DOK1 variants remain in cells of solid tumors and leukemias, albeit, their functions are elusive. To assess the...
Main Authors: | Teresa Friedrich, Michaela Söhn, Tobias Gutting, Klaus-Peter Janssen, Hans-Michael Behrens, Christoph Röcken, Matthias P.A. Ebert, Elke Burgermeister |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-06-01
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Series: | EBioMedicine |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2352396416301864 |
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