The incidence rate of prostate cancer in Saudi Arabia: an observational descriptive epidemiological analysis of data from the Saudi Cancer Registry 2001–2008

Background: This study presents descriptive epidemiological data related to prostate cancer cases diagnosed from 2001 to 2008 among Saudi men, including the frequency and percentage of cases, the crude incidence rate (CIR) and the age-standardised incidence rate (ASIR) adjusted by region and year of...

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Main Authors: Ibrahim G. Alghamidi, Issam I. Hussain, Mohamed S. Alghamdi, Mohammed A. El-Sheemy
Format: Article
Language:English
Published: Elsevier 2014-03-01
Series:Hematology/Oncology and Stem Cell Therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S1658387613000769
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spelling doaj-63f18b1e112b49ffb2b037c1ad89066d2020-11-25T00:19:46ZengElsevierHematology/Oncology and Stem Cell Therapy1658-38762014-03-01711826The incidence rate of prostate cancer in Saudi Arabia: an observational descriptive epidemiological analysis of data from the Saudi Cancer Registry 2001–2008Ibrahim G. Alghamidi0Issam I. Hussain1Mohamed S. Alghamdi2Mohammed A. El-Sheemy3University of Lincoln, Brayford Pool, Lincoln LN6 7TS, UK; Corresponding author. Address: University of Lincoln, School of Life Sciences, Brayford Pool, Lincoln LN6 7TS, UK. Tel.: +44 1162761913, mobile: +44 7547672538.University of Lincoln, Brayford Pool, Lincoln LN6 7TS, UKMinistry of Health, General Directorate of Health Affairs, Al-Baha, Saudi ArabiaUniversity of Lincoln, Brayford Pool, Lincoln LN6 7TS, UK; Lincoln Hospital, Research and Development United, Lincolnshire Hospitals NHS Trust, Lincoln LN2 5QY, UKBackground: This study presents descriptive epidemiological data related to prostate cancer cases diagnosed from 2001 to 2008 among Saudi men, including the frequency and percentage of cases, the crude incidence rate (CIR) and the age-standardised incidence rate (ASIR) adjusted by region and year of diagnosis. Methods: This is a retrospective descriptive epidemiological analysis of all Saudi prostate cancer cases recorded in the Saudi Cancer Registry (SCR) between January 2001 and December 2008. Statistical analyses were conducted using descriptive statistics, the Poisson regression model, a simple linear regression model and analysis of variance with the Statistical Package for the Social Sciences version 20.0 (SPSS). Results: A total of 1739 cases were registered in the SCR between January 2001 and December 2008. The eastern region of Saudi Arabia had the highest overall ASIR at 10.1 per 100,000 men, followed by Riyadh at 7.1 and Makkah at 5.2, while Jizan and Najran had the lowest average ASIRs at 1.4 and at 2.0, respectively. The Poisson regression model for the region of Jizan shows that the incidence rate ratio (IRR) was significantly higher (p < 0.001); for the regions of Riyadh at 3.43 times (95% CI, 3.13–3.73), followed by Makkah at 2.56 (95% CI, 2.38–2.74) and the eastern province at 1.93 (95% CI, 1.64–2.23). The annual prediction of the CIR of prostate cancer in Saudi Arabia could be defined by the equation 1.53 + (0.094 × Years), and the prediction of the ASIR could be defined by the equation 2.98 + (0.182 × Years). Conclusion: There was a steady increase in the CIRs and ASIRs for prostate cancer between 2001 and 2008. The eastern region, Riyadh and Makkah had the highest overall ASIR in Saudi Arabia. Further effective screening programmes and active treatment measures are needed to control prostate cancer disease among Saudi men. Keywords: Epidemiology, Saudi Cancer Registry, Prostate cancer, Crude incidence rate, Age standardised incidence ratehttp://www.sciencedirect.com/science/article/pii/S1658387613000769
collection DOAJ
language English
format Article
sources DOAJ
author Ibrahim G. Alghamidi
Issam I. Hussain
Mohamed S. Alghamdi
Mohammed A. El-Sheemy
spellingShingle Ibrahim G. Alghamidi
Issam I. Hussain
Mohamed S. Alghamdi
Mohammed A. El-Sheemy
The incidence rate of prostate cancer in Saudi Arabia: an observational descriptive epidemiological analysis of data from the Saudi Cancer Registry 2001–2008
Hematology/Oncology and Stem Cell Therapy
author_facet Ibrahim G. Alghamidi
Issam I. Hussain
Mohamed S. Alghamdi
Mohammed A. El-Sheemy
author_sort Ibrahim G. Alghamidi
title The incidence rate of prostate cancer in Saudi Arabia: an observational descriptive epidemiological analysis of data from the Saudi Cancer Registry 2001–2008
title_short The incidence rate of prostate cancer in Saudi Arabia: an observational descriptive epidemiological analysis of data from the Saudi Cancer Registry 2001–2008
title_full The incidence rate of prostate cancer in Saudi Arabia: an observational descriptive epidemiological analysis of data from the Saudi Cancer Registry 2001–2008
title_fullStr The incidence rate of prostate cancer in Saudi Arabia: an observational descriptive epidemiological analysis of data from the Saudi Cancer Registry 2001–2008
title_full_unstemmed The incidence rate of prostate cancer in Saudi Arabia: an observational descriptive epidemiological analysis of data from the Saudi Cancer Registry 2001–2008
title_sort incidence rate of prostate cancer in saudi arabia: an observational descriptive epidemiological analysis of data from the saudi cancer registry 2001–2008
publisher Elsevier
series Hematology/Oncology and Stem Cell Therapy
issn 1658-3876
publishDate 2014-03-01
description Background: This study presents descriptive epidemiological data related to prostate cancer cases diagnosed from 2001 to 2008 among Saudi men, including the frequency and percentage of cases, the crude incidence rate (CIR) and the age-standardised incidence rate (ASIR) adjusted by region and year of diagnosis. Methods: This is a retrospective descriptive epidemiological analysis of all Saudi prostate cancer cases recorded in the Saudi Cancer Registry (SCR) between January 2001 and December 2008. Statistical analyses were conducted using descriptive statistics, the Poisson regression model, a simple linear regression model and analysis of variance with the Statistical Package for the Social Sciences version 20.0 (SPSS). Results: A total of 1739 cases were registered in the SCR between January 2001 and December 2008. The eastern region of Saudi Arabia had the highest overall ASIR at 10.1 per 100,000 men, followed by Riyadh at 7.1 and Makkah at 5.2, while Jizan and Najran had the lowest average ASIRs at 1.4 and at 2.0, respectively. The Poisson regression model for the region of Jizan shows that the incidence rate ratio (IRR) was significantly higher (p < 0.001); for the regions of Riyadh at 3.43 times (95% CI, 3.13–3.73), followed by Makkah at 2.56 (95% CI, 2.38–2.74) and the eastern province at 1.93 (95% CI, 1.64–2.23). The annual prediction of the CIR of prostate cancer in Saudi Arabia could be defined by the equation 1.53 + (0.094 × Years), and the prediction of the ASIR could be defined by the equation 2.98 + (0.182 × Years). Conclusion: There was a steady increase in the CIRs and ASIRs for prostate cancer between 2001 and 2008. The eastern region, Riyadh and Makkah had the highest overall ASIR in Saudi Arabia. Further effective screening programmes and active treatment measures are needed to control prostate cancer disease among Saudi men. Keywords: Epidemiology, Saudi Cancer Registry, Prostate cancer, Crude incidence rate, Age standardised incidence rate
url http://www.sciencedirect.com/science/article/pii/S1658387613000769
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