EGFR modulates complement activation in head and neck squamous cell carcinoma

EGFR modulates complement activation in head and neck squamous cell carcinoma

Abstract Background The epidermal growth factor receptor (EGFR) is pivotal for growth of epithelial cells and is overexpressed in several epithelial cancers like head and neck squamous cell carcinoma (HNSCC). EGFR signalling is also involved in diverse innate immune functions in epithelia. We previo...

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Bibliographic Details
Main Authors: Anas H. A. Abu-Humaidan, Lars Ekblad, Johan Wennerberg, Ole E. Sørensen
Format: Article
Language:English
Published: BMC 2020-02-01
Series:BMC Cancer
Subjects:
EGFR
HNSCC
Complement activation
Complement regulation
Tyrosine kinase inhibitor
Iressa
Online Access:https://doi.org/10.1186/s12885-020-6615-z

Internet

https://doi.org/10.1186/s12885-020-6615-z

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