Structural and advanced imaging in predicting MGMT promoter methylation of primary glioblastoma: a region of interest based analysis

Structural and advanced imaging in predicting MGMT promoter methylation of primary glioblastoma: a region of interest based analysis

Abstract Background The methylation status of oxygen 6-methylguanine-DNA methyltransferase (MGMT) promoter has been associated with treatment response in glioblastoma(GBM). Using pre-operative MRI techniques to predict MGMT promoter methylation status remains inconclusive. In this study, we investig...

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Bibliographic Details
Main Authors:	Yu Han, Lin-Feng Yan, Xi-Bin Wang, Ying-Zhi Sun, Xin Zhang, Zhi-Cheng Liu, Hai-Yan Nan, Yu-Chuan Hu, Yang Yang, Jin Zhang, Ying Yu, Qian Sun, Qiang Tian, Bo Hu, Gang Xiao, Wen Wang, Guang-Bin Cui
Format:	Article
Language:	English
Published:	BMC 2018-02-01
Series:	BMC Cancer
Subjects:	Glioblastoma Image feature Oxygen 6-methylguanine-DNA methyltransferase (MGMT) promoter Apparent diffusion coefficient (ADC) 3-diminsional pseudo-continuous arterial spin labeling (3D pCASL) imaging
Online Access:	http://link.springer.com/article/10.1186/s12885-018-4114-2

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