Synthetic studies towards bottromycin

Synthetic studies towards bottromycin

Thio-Ugi reactions are described as an excellent synthetic tool for the synthesis of sterically highly hindered endothiopeptides. S-Methylation and subsequent amidine formation can be carried out in an inter- as well as in an intramolecular fashion. The intramolecular approach allows the synthesis o...

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Bibliographic Details
Main Authors:	Stefanie Ackermann, Hans-Georg Lerchen, Dieter Häbich, Angelika Ullrich, Uli Kazmaier
Format:	Article
Language:	English
Published:	Beilstein-Institut 2012-10-01
Series:	Beilstein Journal of Organic Chemistry
Subjects:	amidines antibiotics bottromycin peptides thiopeptides Ugi reactions
Online Access:	https://doi.org/10.3762/bjoc.8.189

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