Regulation of the formyl peptide receptor 1 (FPR1) gene in primary human macrophages.

Regulation of the formyl peptide receptor 1 (FPR1) gene in primary human macrophages.

The formyl peptide receptor 1 (FPR1) is mainly expressed by mammalian phagocytic leukocytes and plays a role in chemotaxis, killing of microorganisms through phagocytosis, and the generation of reactive oxygen species. A large number of ligands have been identified triggering FPR1 including formylat...

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Bibliographic Details
Main Authors: Claudio Gemperle, Mattia Schmid, Magdalena Herova, Jacqueline Marti-Jaun, Sophia J A Wuest, Christa Loretz, Martin Hersberger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3503994?pdf=render

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