Medico-genetic counseling in primary arrhythmia prevention

• Main Authors: I. G. Fomina, N. P. Kuleshov, L. V. Logunova, N. B. Morgunov, A. I. Tarzimanova
• Format: Article
• Language: Russian
• Published: «SILICEA-POLIGRAF» LLC 1970-01-01
• Series: Кардиоваскулярная терапия и профилактика
• Subjects: premature ventricular complex syndrome; medico-genetic counseling; primary arrhythmia prevention; inheritance of wolf-parkinson-white syndrome
• Online Access: https://cardiovascular.elpub.ru/jour/article/view/1489
• ISSN: 1728-8800; 2619-0125

Aim. To assess the role of medico-genetic counseling in diagnostics of the insufficiently explored premature ventricular complex (PVC) syndrome. Material and methods. Medico-genetic counseling and prospective follow-up (1973-present) was performed in the families of 36 patients with Wolf-Parkinson-White (WPW) syndrome (222 relatives examined), and in the families of 40 patients with Clerc-Levy-Cristesco (CLC) syndrome (227 relatives examined). Results. PVC phenomenon in I-IV line relatives was regarded as a manifestation of hereditary arrhythmia predis-position and an indication for preventive measures, electrocardiographic assessment included. Healthy relatives were examined at least every 6-months, then once per year, including psychotherapeutic counseling on lifestyle modification. During the 30-year follow-up period, PVC patients’ relatives complying with healthy lifestyle recommendations did not have any complaints and regarded themselves as healthy persons. Conclusion. Therefore, medico-genetic counseling is the most sensitive method for PVC syndrome diagnostics. Widely available psychotherapeutic counseling on healthy lifestyle facilitates the healthy status maintenance in III-IV line relatives.