Extracellular Vesicles Act as Nano-Transporters of Tyrosine Kinase Inhibitors to Revert Iodine Avidity in Thyroid Cancer

Extracellular Vesicles Act as Nano-Transporters of Tyrosine Kinase Inhibitors to Revert Iodine Avidity in Thyroid Cancer

A new approach for using extracellular vesicles (EVs) to deliver tyrosine kinase inhibitors (TKIs) to enhance iodine avidity in radioactive iodine-refractory thyroid cancer is needed. We isolated and characterized primary human adipose-derived stem cells (ADSCs) and isolated their EVs. The EVs were...

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Bibliographic Details
Main Authors: Ramya Lakshmi Rajendran, Sanjita Paudel, Prakash Gangadaran, Ji Min Oh, Eun Jung Oh, Chae Moon Hong, Sangkyu Lee, Ho Yun Chung, Jaetae Lee, Byeong-Cheol Ahn
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Pharmaceutics
Subjects:
extracellular vesicles
tyrosine kinase inhibitor
drug delivery
radioactive iodine
thyroid cancer
Online Access:https://www.mdpi.com/1999-4923/13/2/248

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