An Efficient Approach to Screening Epigenome-Wide Data

Screening cytosine-phosphate-guanine dinucleotide (CpG) DNA methylation sites in association with some covariate(s) is desired due to high dimensionality. We incorporate surrogate variable analyses (SVAs) into (ordinary or robust) linear regressions and utilize training and testing samples for neste...

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Bibliographic Details
Main Authors: Meredith A. Ray, Xin Tong, Gabrielle A. Lockett, Hongmei Zhang, Wilfried J. J. Karmaus
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2016/2615348