Stress-induced cell-cycle activation in Tip60 haploinsufficient adult cardiomyocytes.

Tat-interactive protein 60 (Tip60) is a member of the MYST family of histone acetyltransferases. Studies using cultured cells have shown that Tip60 has various functions including DNA repair, apoptosis and cell-cycle regulation. We globally ablated the Tip60 gene (Htatip), observing that Tip60-null...

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Bibliographic Details
Main Authors: Joseph B Fisher, Min-Su Kim, Steven Blinka, Zhi-Dong Ge, Tina Wan, Christine Duris, Desirae Christian, Kirk Twaroski, Paula North, John Auchampach, John Lough
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3279378?pdf=render