Anti-high mobility group box 1 antibody suppresses local inflammatory reaction and facilitates olfactory nerve recovery following injury

Anti-high mobility group box 1 antibody suppresses local inflammatory reaction and facilitates olfactory nerve recovery following injury

Abstract Background Refractory olfactory dysfunction is a common finding in head trauma due to olfactory nerve injury. Anti-inflammatory treatment using steroids is known to contribute to functional recovery of the central and peripheral nervous systems in injury models, while there is a concern tha...

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Bibliographic Details
Main Authors: Masayoshi Kobayashi, Kengo Tamari, Mohammed Omar Al Salihi, Kohei Nishida, Kazuhiko Takeuchi
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Journal of Neuroinflammation
Subjects:
Astrocyte
Cycloheximide
Field potential recording
Head injury
HMGB1
Macrophage
Online Access:http://link.springer.com/article/10.1186/s12974-018-1168-7

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