Human Neural Stem Cells Overexpressing Choline Acetyltransferase Restore Cognitive Function of Kainic Acid-Induced Learning and Memory Deficit Animals

Human Neural Stem Cells Overexpressing Choline Acetyltransferase Restore Cognitive Function of Kainic Acid-Induced Learning and Memory Deficit Animals

Alzheimer disease (AD) is a progressive neurodegenerative disease, which is characterized by loss of memory and cognitive function. In AD patients dysfunction of the cholinergic system is the main cause of cognitive disorders, and decreased activity of choline acetyltransferase (ChAT), an enzyme res...

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Bibliographic Details
Main Authors:	Dongsun Park, Seong Soo Joo, Tae Kyun Kim, Sun Hee Lee, Hyomin Kang, Hong Jun Lee, Inja Lim, Akinori Matsuo, Ikuo Tooyama, Yun-Bae Kim, Seung U. Kim
Format:	Article
Language:	English
Published:	SAGE Publishing 2012-02-01
Series:	Cell Transplantation
Online Access:	https://doi.org/10.3727/096368911X586765

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