Assessing the public health impact of tolerance-based therapies with mathematical models.
Disease tolerance is a defense strategy against infections that aims at maintaining host health even at high pathogen replication or load. Tolerance mechanisms are currently intensively studied with the long-term goal of exploiting them therapeutically. Because tolerance-based treatment imposes less...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-05-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC5955582?pdf=render |