Simple In-House Fabrication of Microwells for Generating Uniform Hepatic Multicellular Cancer Aggregates and Discovering Novel Therapeutics

Simple In-House Fabrication of Microwells for Generating Uniform Hepatic Multicellular Cancer Aggregates and Discovering Novel Therapeutics

Three-dimensional (3D) cell culture models have become powerful tools because they better simulate the in vivo pathophysiological microenvironment than traditional two-dimensional (2D) monolayer cultures. Tumor cells cultured in a 3D system as multicellular cancer aggregates (MCAs) recapitulate seve...

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Bibliographic Details
Main Authors:	Chiao-Yi Chiu, Ying-Chi Chen, Kuang-Wei Wu, Wen-Chien Hsu, Hong-Ping Lin, Hsien-Chang Chang, Yung-Chun Lee, Yang-Kao Wang, Ting-Yuan Tu
Format:	Article
Language:	English
Published:	MDPI AG 2019-10-01
Series:	Materials
Subjects:	multicellular cancer aggregates multicellular tumor spheroids microwell liver cancer doxorubicin photothermal treatment
Online Access:	https://www.mdpi.com/1996-1944/12/20/3308

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