Non-canonical PD-1 signaling in cancer and its potential implications in clinic
Programmed cell death 1 (PD-1)-based immunotherapy has revolutionized the treatment of various cancers. However, only a certain group of patients benefit from PD-1 blockade therapy and many patients succumb to hyperprogressive disease. Although, CD8 T cells and conventional T cells are generally con...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMJ Publishing Group
2021-02-01
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Series: | Journal for ImmunoTherapy of Cancer |
Online Access: | https://jitc.bmj.com/content/9/2/e001230.full |