IFNL3 rs12980275 Polymorphism Predicts Septic Shock-Related Death in Patients Undergoing Major Surgery: A Retrospective Study

IFNL3 rs12980275 Polymorphism Predicts Septic Shock-Related Death in Patients Undergoing Major Surgery: A Retrospective Study

Interferon lambda 3 (IFNL3, previously called IL-28B) is a cytokine with effects against viral and bacterial pathogens. We aimed to analyze the IFNL3 rs12980275 SNP in patients who underwent major surgery, in order to establish its relationship with susceptibility to septic shock and septic shock-re...

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Bibliographic Details
Main Authors: Felipe Pérez-García, Maria Ángeles Jiménez-Sousa, Susana Soria, Pablo Jorge-Monjas, Amanda Fernández-Rodríguez, Esther Gómez-Sánchez, María Heredia-Rodríguez, Estefanía Gómez-Pesquera, Pedro Martínez-Paz, Eduardo Tamayo, Salvador Resino
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Medicine
Subjects:
IFNL3
rs12980275
SNP
sepsis
septic shock
survival
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2020.00186/full

Internet

https://www.frontiersin.org/article/10.3389/fmed.2020.00186/full

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