Relation between clinical and anthropometric data and systemic inflammation in patients with COPD.

• Main Authors: Т. А. Pertseva, D. S. Mykhailychenko
• Format: Article
• Language: English
• Published: SE "Dnipropetrovsk medical academy of Health Ministry of Ukraine" 2015-11-01
• Series: Medičnì Perspektivi
• Subjects: chronic obstructive pulmonary disease; systemic inflammation; C-reactive protein
• Online Access: http://journals.uran.ua/index.php/2307-0404/article/view/56128

Recently, much attention is devoted to systemic inflammation in patients with chronic obstructive pulmonary disease (COPD). The aim of our study was to determine the relationship between clinical and anthropometric data with systemic inflammation in  stable COPD patients. According to the study CRP levels were raised in 44% of patients(7.9 [7,1-10,9). Serum CRP was significantly higher in stable COPD patients than in control subjects (p=0.04). CRP correlated well with the pack/yearsindex(p = 0,032) and disease duration (p=0,01). It wasn’t established link between CRP levels and height, weight, stage, disease category. CRP level affected the frequency of exacerbations (r=0,50; p=0,01). Patients with high CRP level had significantly more exacerbations in the past year (p=0.01). Patients who received any type of therapyfor a long period of time had lower CRP levels, than patients who did not reseive any therapy.